Sometimes, the greatest gift you can give to a homeless pet is time, love, and a temporary place to call home.

Great Pyrenees Rescue of Missouri is a state-licensed, 501(c)(3), foster-based rescue dedicated to saving all Great Pyrenees who are without a home, need medical attention or need a safe-haven as they await their forever home. All of the Great Pyrenees in our care live in foster homes until a forever home can be found. We rescue without regard to health, age, or ease of placement.

We are committed to placing 100% of adoptable Pyrs into new homes, and providing these dogs who enter our care with the resources they need to be happy, healthy, and ultimately, find new homes.

It is only through the generosity of donations that we are able to help lost, abandoned and abused dogs in Missouri and surrounding states. A special thanks to those who support Great Pyrenees Rescue of Missouri!

Featured foster

Cain has a goofy, playful personality - he's just shy of a year old and about 90 lbs. He is pretty active and needs another playful dog in the home to help him burn off some energy.


He likes toys and things to chew on, especially deer antler bones. Cain loves pets and loves when you love on him. Watch out for his big Pyr paw! And keep the toilet lid closed or he's bound to take a drink. He's messy with his water bowl and when he eats his food so he needs a home that is tolerant of that. Cain would make a great family dog; he loves children. Cain is crate trained and potty trained.

Are you ready to add a goofy pup to your family?

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sponsor a pyr

Can't adopt right now, but still want to help? By sponsoring a dog, you’ll not only change their life, but you’ll also help us save the lives of many other dogs in need. Your monthly gift will help fund food, monthly preventatives, glucosamine, prescription medications, and veterinary care.  We have some sanctuary dogs and dogs that have been in rescue since 2020 that we could really use your help with their monthly expenses. On average we incur a monthly expense of $100 per dog. 


Sponsor a Senior

Phoenix and Sundance are 9-10 year old Great Pyrenees mix brothers that were surrendered to an Arkansas shelter due to a family illness. They have been with us since 2020 and are happy in their foster home. We feel that neither boy would make the transition to a new home well so we will love and take care of them for as long as they are with us.


Pyrs With Their Furever Families


Find Your New Best Friend!


Give The Gift Of A Second Chance


Open Your Heart And Home To A Pyr In Need


You Are What Makes This Rescue Grow